Always start with Overstock.com
We've gotten 800 TC Egyptian cotton king size sheet sets for $70.00; a pair of $300 Porsche sunglasses for $80.00. A steel and brass queen sized bed we saw in stores for $700.00 for $250.00; and a $450.00 Tiffany knock-off bedside lamp for $99.00.
Pet medications
Frontline, Heartgard, Revolution; any pet meds you need for around half price.
Pet toys, shampoo, leashes, and grooming stuff.
Medications cost more than Petsupply.com, but other non-med stuff is great.
Electronics
Got my HDTV delivered, with the stand from B&H for $800 less than Best Buy wanted for the TV alone without delivery. Always check thenm both.
Digital Cameras
$100-$300 less than Best Buy for the better cameras.
Books (If you can wait till it's off the best seller lists)
If it was published more than a year ago, try here first; you can save 80%
Books (Best Sellers)
Usually a dollar or two cheaper than Amazon.com
Men's clothing - Joseph A. Bank
If you can wait 6 months to wear it, these people have amazing "end of season" on-line sales on suits, slacks, sports coats, shirts, ties, you name it. Last spring I got two wool and one camelhair sports coats that I had looked at when they were $395 -$495 for $92.00 each.
Junior's Cheesecake
A little pricy, but OH MY GOD!!!!!!!!!!!!!!!
Chocolate for us
My wife and I give each other monster gift baskets.
Chocolate for others
I don't want to hear from you SF people, I love Ghirardelli, but we are from KC.
Wine Country gift basket.
I just received a gift basket from an engineer I helped trouble shoot a project. It has four bottles of Grgich Hills wine (Is it any good, Noah?), and about a thousand packages of crackers, cheese spread, cookies, Ghiradelli chocolate, and nuts. All packed in a cool twig and wicker basket. I get a few worthless crap baskets from clients at Christmas; but this one has potential. What a great gift.
OnMyList
List your pants off!